四氟化硅

1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)

 

 

1. Product Name: selectfluor fluorinating reagent

Chinese Chemical name: 1-氯甲基-4-氟-1,4-二氮杂双环[2.2.2]辛烷二(四氟硼酸)盐

English chemical name: SELECTFLUOR FLUORINATING REAGENT (Selectfluor)

Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)

2. Molecular formula: C7H14B2ClF9N2

3. CAS NO：140681-55-6

4. Molecular Weight: 354.26

5. Product Uses:

     Selectfluor is a stable and mild fluorinated reagent, for the substitution of fluorides such as fluorine and perchloryl fluoride. It can lead fluorine atoms into carbonyl ortho-position of organic molecules. So it is an important method of leading fluorine atoms into drug. Selectfluor can generate single fluorination reaction on electron-rich double bond, silyl enol ethers, and enol lithium salt, which is mainly used for leading fluorine atoms into steroidal drug molecules in domestic and foreign market. 

     (1) Selectfluor can generate electrophilic fluorination reaction on aldehydes, ketones, esters and other substrates.

     (2) As a fluorinated reagent, Selectfluor can generate additive reaction on double bond.

     (3) As a fluorinated reagent, Selectfluor can be used for the fluorination of aromatic compounds.

     (4) As a fluorinated reagent, Selectfluor can be used for the fluorination of steroidal drugs.

6. Product Specifications:

     White crystals, melting point: 260 ° C; purity is greater than 98%.

7. Competitiveness of Product:

     Selectfluor is a new kind of product emerging in recent years, which comply with national safety, environmental protection and export encouragement policies. Fluorinating with fluorine is the most important link of producing NFSI. While for non-nuclear corporation, it is a technical bottleneck to produce fluorine and further control it safely, steadily and effectively. Our company cooperates with relevant nuclear institutes,has professional technicians of electrolytic fluorine and stable equipment of fluoride electrolysis----electrolyzer, can produce large quantities of fluorine with high-purity and control fluorine safely, steadily and effectively. So the advantage of cost of raw materials is obvious. At present, besides our company, there is no large-scale manufacturer of NFSI in domestic, while there is only one manufacturer at abroad, and the cost is higher. Meanwhile, relying on well-known universities, we have technical advantages as well. Therefore, both the product quality and the scale production capacity of our company are leading in international and domestic.

Chemical Safety Data Sheet of Selectfluor (MSDS)

1. Chemical Name

Chinese chemical name: 1-氯甲基-4-氟-1,4-二氮杂双环[2.2.2]辛烷二(四氟硼酸)盐

English chemical name:

1-(Chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)

2. Molecular Formula: C7H14B2ClF9N2

3. CAS NO: 140681-55-6

4. Molecular Weight: 354.26

5. Ingredient/Composition Information

1 - (chloromethyl) -4 - fluoro-1 ,4 - diazabicyclo [2.2.2] octane bis (tetrafluoroborate) salt:> 98%

6. Risk Description

Hazard Symbol: Xn (harmful substance)

Hazard Categories:

     (1) It will be harmful if swallowed.

     (2) Risk of serious injury to the eye.

     (3) May cause allergy through contact with skin.

     (4) Harmful to aquatic organisms and may cause long-term adverse effects to aquatic environment.

7. Emergency Measures

     (1) Do not smoke when using.

     (2) In the event of contact with eyes, flush immediately with plenty of water and consult the doctor for suggestion.

     (3) Wear suitable protective clothing, gloves and eye / face protection equipment.

     (4) Avoid discarding in surrounding environment.

8. Physical and Chemical Properties

Appearance: white powder

Odor: no special smell

Melting point: 260 ° C

Decomposition temperature: > 50 ° C

Risk of explosion: There is no risk of explosion.

9. Transport Information

     UN “Standard Requirements”: UN3088

     Transport/Additional Information: According to the above specifications, it is not dangerous, and belongs to non-regulated hazardous chemicals.

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